Fungal Endophytes as Efficient Sources of Plant-Derived Bioactive Compounds and Their Prospective Applications in Natural Product Drug Discovery: Insights, Avenues, and Challenges.

摘要: Fungal endophytes are well-established sources of biologically active natural compounds with many producing pharmacologically valuable specific plant-derived products. This review details typical medicinal several classes, including alkaloids, coumarins, flavonoids, glycosides, lignans, phenylpropanoids, quinones, saponins, terpenoids, and xanthones that produced by endophytic fungi. covers the studies carried out since first report taxol biosynthesis Taxomyces andreanae in 1993 up to mid-2020. The article also highlights prospects endophyte-dependent such bottlenecks commercialization this novel approach area drug discovery. After recent updates field ‘omics’ ‘one strain compounds’ (OSMAC) approach, fungal have emerged as strong unconventional source prized