Compound and compositions as TGR5 agonists: WO2012082947
作者： Saurin Raval
DOI: 10.1517/13543776.2013.770841
关键词:
摘要: The patent application WO2012082947 claims novel compounds as agonists of a plasma membrane-bound bile acid receptor TGR5. By activating TGR5, the improve glycemic control and enhance energy expenditure. basic generic claim covers pyrazole derivatives, different permutations on core ring are covered in subsidiary claims. claimed human TGR5 having potency nM range.
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