3-amino-pyridines as gpbar1 agonists
作者： Christoph Ullmer , Hans Richter , Henrietta Dehmlow , Patrizio Mattei , Sherrie Lynn Pietranico-Cole
DOI:
关键词:
摘要: This invention relates to novel 3-aminopyridines of the formula (I) wherein B1, B2 and R1 R6 are as defined in description claims, well pharmaceutically acceptable salts thereof. These compounds GPBAR1 agonists can be used medicaments for treatment diseases such type II diabetes.
lens.org 参考文章(24)
Yasunori Moritani, Akira Oku, Yasunori Tsuboi, Shigeru Furukubo, Naomitsu Hirano, Chieko Okagaki, Pyrrolidine derivatives as cb1-receptor antagonists ,(2005)
Boronic acids : preparation and applications in organic synthesis and medicine WILEY-VCH Verlag. ,(2005) , 10.1002/3527606548
J. F. W. McOmie, Protective Groups in Organic Chemistry ,(2012)
Junichi Yasuoka, Tetsuya Ikemoto, Yosuke Watanabe, Manufacturing method for a piperidine-3-ylcarbamate compound and optical resolution method therefor ,(2009)
Metal-catalyzed cross-coupling reactions Wiley-VCH. ,(2004) , 10.1002/9783527619535
Andreas Koblet, Jens-Uwe Peters, Patrick Schnider, Andrew Sleight, Heinz Stadler, Torsten Hoffmann, Dual nk1/nk3 antagonists for treating schizophrenia ,(2004)
Richard C. Larock, Comprehensive organic transformations : a guide to functional group preparations Wiley-VCH. ,(2018) , 10.1002/9781118662083
Timothy J. Guzi, Praveen K. Tadikonda, Tzu Tshin Wong, Lianyun Zhao, Panduranga Adulla P. Reddy, Luis E. Torres, M. Arshad Siddiqui, David F. Cauble, Shuyi Tang, Heterocyclic amide compounds as protein kinase inhibitors ,(2008)
Tanya Michelle Jewell, John Howard Tatlock, Angelica Linton, Hui Li, Javier Gonzalez, Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same ,(2005)
Niko Schmiedeberg, Klemens Högenauer, Herbert Jaksche, Luca Arista, Gudrun Werner, Amide derivatives and their application for the treatment of g protein related diseases ,(2007)