Novel kif5b-ret fusion molecules and uses thereof
作者： Matthew J. Hawryluk , Sean R. Downing , Doron Lipson , Alexander N. Parker , Philip James Stephens
DOI:
关键词:
摘要: Novel RET fusion molecules and uses are disclosed. In one embodiment, a KIF5B-RET includes an in-frame of exon KIF5B (e.g., more exons encoding kinesin motor domain or fragment thereof) tyrosine kinase thereof). For example, the can include at least 15 thereof 1-15 with ex on 12 12-20 5
lens.org 参考文章(86)
R. A. Reisfeld, S. Sell, Monoclonal antibodies and cancer therapy UCLA symposium on molecular and cellular biology. Annual meeting. 14. pp. 33- 74 ,(1985)
Jung-Tang Huang, Cheng-Hung Tsai, Ultra-rapid DNA sequencing method with nano-transistors array based devices ,(2006)
Koji Tsuta, Takashi Kohno, Fusion gene of kif5b gene and ret gene, and method for determining effectiveness of cancer treatment targeting fusion gene ,(2012)
Roman Yelensky, Sean R. Downing, Mirna Jarosz, Mikhail G. Shapiro, Doron Lipson, Philip James Stephens, Geoffrey Alan Otto, Alexander N. Parker, Optimization of multigene analysis of tumor samples ,(2011)
Larry E. Morrison, Mona S. Legator, Michael L. Bittner, Methods for multiple direct label probe detection of multiple chromosomes or regions thereof by in situ hybridization ,(1998)
Daisy Wing-Sze Wong, Elaine Lai-Han Leung, Sunny Kit-Man Wong, Vicky Pui-Chi Tin, Alan Dart-Loon Sihoe, Lik-Cheung Cheng, Joseph Siu-Kie Au, Lap-Ping Chung, Maria Pik Wong, A novel KIF5B-ALK variant in nonsmall cell lung cancer. Cancer. ,vol. 117, pp. 2709- 2718 ,(2011) , 10.1002/CNCR.25843
James Ferrell, Jason Myers, Methods and compositions for use in preparing sirnas ,(2003)
John Bright, Bishwajit Nag, Subramaniam Sriram, Somesh D. Sharma, Protein kinase inhibitor ,(1998)
Robert Coopersmith, Raphael Lehrer, Individualized cancer treatment ,(2009)