Method using a ret fusion gene as a biomarker to select non-small cell lung cancer (nsclc) and thyroid cancer patients for a cancer treatment
作者： Kaoru Tanaka , Kunio Okamoto , Kazuko Sakai , Toshio Shimizu , Kazuhiko Nakagawa
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摘要: The present invention relates to a RET fusion gene such as CCDC6-RET biomarker monitor the activity of compound 3-Z-[1-(4-(N-((4-methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylene]-6-methoxycarbonyl-2-indolinone or pharmaceutically acceptable salt thereof, and especially its monoethanesulphonate form, when used alone optionally in combination with further active ingredients and/or treatments. also specific uses said treatment cancers.
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