Alcohol- and water-based extracts obtained from Rhodiola rosea affect differently the number and metabolic activity of circulating granulocytes in Balb/c mice
作者： Ewa Skopińska-Różewska , Robert Zdanowski , Przemysław Michał Mrozikiewicz , Sławomir Lewicki , Wanda Stankiewicz
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摘要: Introduction and objective. Rhodiola rosea (RR) rhizomes with root extracts are traditional natural drugs originating from Asia now commonly used as adaptogens antidepressants. The aim of the presented study was to examine in vivo effect aqueous (RRW) 50% hydro-alcoholic (RRA) on number metabolic activity blood granulocytes mice. Material methods . Mice were fed for 7 days RR extract at daily doses 0.05, 0.1, 0.2 or 0.4 mg. determined by measuring their luminol-dependent chemiluminescent a scintillation counter, after zymosan stimulation. Results. diminished chemiluminescence enhanced all groups mice R.rosea extract. Aqueous ineffective applied. Conclusion revealed difference RRA RRW extracts. Immune characteristics some individual compounds extracts, selected HPLC analysis, should be carried out subsequent experiments.
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