P2X Receptors for ATP: Classification, Distribution, and Function

作者: R. J. Evans

DOI: 10.1007/978-3-642-57083-4_20

关键词:

摘要: P2 receptors for ATP may be subclassified into ligand gated P2X receptor cation channels and metabotropic G-protein coupled P2Y receptors. can released from a variety of cell types including neurons (VON KUGELGEN STARKE 1991; SILINSKY REDMAN1996) endothelial cells (YANGet al. 1994; BODIN BURNSTOCK 1996) or as result local tissue damage lysis (BURNSTOCK 1996). mediate fast synaptic transmission between in the periphery (EVANS et 1992; GALLIGAN BERTRAND 1995), central nervous system (EDWARDS al.1992), sympathetic nerves smooth muscle SURPRENANT 1992). In addition are expressed ranging immune to cochlear hair (BUELL 1996a; RAYBOULD HOUSLEY 1997). The aim this chapter is give an overview properties distribution cloned how corresponds native phenotypes.

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