Use of erythropoietin for scar-free healing of wounds or tissue defects
作者： Augustinus Bader
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摘要: The invention relates to a novel therapeutic principle for regenerating skin, causing significantly less scarring during wound healing, in particular large wounds, wounds resulting from severe burns, and non-healing wounds. particularly the use effect of erythropoietin (EPO) combination with endogenous or exogenous trauma-induced cytokines on stem cells dermal carrying CD90.
lens.org 参考文章(12)
Augustinus Bader, Topical application and formulation of erythropoietin for skin wound healing ,(2008)
Augustinus Bader, Tissue regeneration method ,(2004)
Saher Hamed, Beyond hematopoietic targets: the role of erythropoietin in diabetic wound healing. Biomarkers in Medicine. ,vol. 5, pp. 365- 367 ,(2011) , 10.2217/BMM.11.30
Saher Hamed, Yehuda Ullmann, Muhannad Masoud, Elias Hellou, Ziad Khamaysi, Luc Teot, Topical erythropoietin promotes wound repair in diabetic rats. Journal of Investigative Dermatology. ,vol. 130, pp. 287- 294 ,(2010) , 10.1038/JID.2009.219
Yerem Yeghiazarians, Muhammad Khan, Franca S Angeli, Yan Zhang, Sarah Jahn, Megha Prasad, Rachel Mirsky, Henry Shih, Petros Minasi, Andrew Boyle, William Grossman, None, Cytokine combination therapy with long-acting erythropoietin and granulocyte colony stimulating factor improves cardiac function but is not superior than monotherapy in a mouse model of acute myocardial infarction. Journal of Cardiac Failure. ,vol. 16, pp. 669- 678 ,(2010) , 10.1016/J.CARDFAIL.2010.03.008
Augustinus Bader, Sanja Pavlica, Andrea Deiwick, Halka Lotkova, Otto Kucera, Kai Darsow, Sebastian Bartel, Mattes Schulze, Harald A. Lange, Zuzana Cervinkova, Proteomic analysis to display the effect of low doses of erythropoietin on rat liver regeneration. Life Sciences. ,vol. 89, pp. 827- 833 ,(2011) , 10.1016/J.LFS.2011.08.002
Augustinus Bader, Hans-Guenther Machens, Recombinant Human Erythropoietin Plays a Pivotal Role As a Topical Stem Cell Activator to Reverse Effects of Damage to the Skin in Aging and Trauma Rejuvenation Research. ,vol. 13, pp. 499- 500 ,(2010) , 10.1089/REJ.2010.1064
Augustinus Bader, Katrin Lorenz, Anja Richter, Katja Scheffler, Larissa Kern, Sabine Ebert, Shibashish Giri, Maria Behrens, Ulf Dornseifer, Paolo Macchiarini, Hans-Günther Machens, Interactive Role of Trauma Cytokines and Erythropoietin and Their Therapeutic Potential for Acute and Chronic Wounds Rejuvenation Research. ,vol. 14, pp. 57- 66 ,(2011) , 10.1089/REJ.2010.1050
Heiko Sorg, Christian Krueger, Torsten Schulz, Michael D. Menger, Frank Schmitz, Brigitte Vollmar, Effects of erythropoietin in skin wound healing are dose related The FASEB Journal. ,vol. 23, pp. 3049- 3058 ,(2009) , 10.1096/FJ.08-109991