A Glycopeptide from the Posterior Lobe of Pig Pituitaries

作者: Dirk A. Holwerda

DOI: 10.1111/J.1432-1033.1972.TB01918.X

关键词:

摘要: An extract from the posterior lobes of pig pituitaries contains a glycopeptide with molecular mass 3200 (± 5%). The is present in amounts same order as hormones oxytocin and vasopressin. The peptide portion composed seventeen amino acid residues: aspartic or asparagine (3), threonine (1), serine proline glycine (2), alanine leucine (3) arginine (1). carbohydrate portion, about 55% by weight, fucose galactose mannose glucosamine (4). exhibits none known physiological activities hypophysis except for slight lipolytic activity.

参考文章(27)
Th. J. Penders, J. F. Arens, Isolation of O-acetyltyrosylvaline from pig neurohypophysis Experientia. ,vol. 22, pp. 722- 723 ,(1966) , 10.1007/BF01901339
Roman Dreywood, Qualitative Test for Carbohydrate Material Industrial & Engineering Chemistry Analytical Edition. ,vol. 18, pp. 499- 499 ,(1946) , 10.1021/I560156A015
H. Tuppy, The amino-acid sequence in oxytocin. Biochimica et Biophysica Acta. ,vol. 11, pp. 449- 450 ,(1953) , 10.1016/0006-3002(53)90071-7
Pehr Edman, Erik Högfeldt, Lars Gunnar Sillén, Per-Olof Kinell, Method for Determination of the Amino Acid Sequence in Peptides. Acta Chemica Scandinavica. ,vol. 4, pp. 283- 293 ,(1950) , 10.3891/ACTA.CHEM.SCAND.04-0283
Karl A. Piez, Louise Morris, A modified procedure for the automatic analysis of amino acids. Analytical Biochemistry. ,vol. 1, pp. 187- 201 ,(1960) , 10.1016/0003-2697(60)90045-2
T. Winnick, R.E. Winnick, R. Acher, C. Fromageot, Amino acids and peptides of posterior pituitary and hypothalamus tissues Biochimica et Biophysica Acta. ,vol. 18, pp. 488- 494 ,(1955) , 10.1016/0006-3002(55)90139-6
Daniel Rudman, Alejandro Del Rio, Luis A. Garcia, John Barnett, Carolyn H. Howard, William Walker, Gary Moore, Isolation of two lipolytic pituitary peptides. Biochemistry. ,vol. 9, pp. 99- 108 ,(1970) , 10.1021/BI00803A013
Pehr Edman, K. J. Björkqvist, R. Reiter, E. Schønfeldt, Inger Steensgaard, Th. Rosenberg, Note on the Stepwise Degradation of Peptides via Phenyl Thiohydantoins. Acta Chemica Scandinavica. ,vol. 7, pp. 700- 701 ,(1953) , 10.3891/ACTA.CHEM.SCAND.07-0700