The Great Debate at ‘Immunotherapy Bridge’, Naples, December 5, 2019
作者： Paolo A Ascierto , Carlo Bifulco , Jerome Galon , Claus Garbe , Samir N Khleif
关键词:
摘要: As part of the 2019 Immunotherapy Bridge congress (December 4-5, Naples, Italy), Great Debate session featured counterpoint views from leading experts on six topical issues in immunotherapy today. These were use chimeric antigen receptor T cell therapy solid tumors, whether Immunoscore should be more widely used clinical practice, antibody-dependent cellular cytotoxicity is important mode action anticytotoxic T-lymphocyte-associated protein 4 antibodies, brain immunologically unique or just another organ, role microbiome versus nutrition affecting responses to immunotherapy, and chemotherapy immunostimulatory immunosuppressive. Discussion these topics are summarized this report.
psjhealth.org
elsevier.com参考文章(52)
Li Wu, Zhen Chen, Jian Zhang, Yiqiao Xing, Effect of miR-513a-5p on etoposide-stimulating B7-H1 expression in retinoblastoma cells Journal of Huazhong University of Science and Technology [Medical Sciences]. ,vol. 32, pp. 601- 606 ,(2012) , 10.1007/S11596-012-1004-8
Gary D Wu, Jun Chen, Christian Hoffmann, Kyle Bittinger, Ying-Yu Chen, Sue A Keilbaugh, Meenakshi Bewtra, Dan Knights, William A Walters, Rob Knight, Rohini Sinha, Erin Gilroy, Kernika Gupta, Robert Baldassano, Lisa Nessel, Hongzhe Li, Frederic D Bushman, James D Lewis, Linking Long-Term Dietary Patterns with Gut Microbial Enterotypes Science. ,vol. 334, pp. 105- 108 ,(2011) , 10.1126/SCIENCE.1208344
Hélène Bugaut, Mélanie Bruchard, Hélène Berger, Valentin Derangère, Ludivine Odoul, Romain Euvrard, Sylvain Ladoire, Fanny Chalmin, Frédérique Végran, Cédric Rébé, Lionel Apetoh, François Ghiringhelli, Grégoire Mignot, Bleomycin Exerts Ambivalent Antitumor Immune Effect by Triggering Both Immunogenic Cell Death and Proliferation of Regulatory T Cells PLoS ONE. ,vol. 8, pp. e65181- ,(2013) , 10.1371/JOURNAL.PONE.0065181
C Marcela Diaz-Montero, Mohamed Labib Salem, Michael I Nishimura, Elizabeth Garrett-Mayer, David J Cole, Alberto J Montero, None, Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy Cancer Immunology, Immunotherapy. ,vol. 58, pp. 49- 59 ,(2009) , 10.1007/S00262-008-0523-4
Paul C. Tumeh, Christina L. Harview, Jennifer H. Yearley, I. Peter Shintaku, Emma J. M. Taylor, Lidia Robert, Bartosz Chmielowski, Marko Spasic, Gina Henry, Voicu Ciobanu, Alisha N. West, Manuel Carmona, Christine Kivork, Elizabeth Seja, Grace Cherry, Antonio J. Gutierrez, Tristan R. Grogan, Christine Mateus, Gorana Tomasic, John A. Glaspy, Ryan O. Emerson, Harlan Robins, Robert H. Pierce, David A. Elashoff, Caroline Robert, Antoni Ribas, PD-1 blockade induces responses by inhibiting adaptive immune resistance Nature. ,vol. 515, pp. 568- 571 ,(2014) , 10.1038/NATURE13954
Owen T. M. Chan, Li-Xi Yang, The immunological effects of taxanes. Cancer Immunology, Immunotherapy. ,vol. 49, pp. 181- 185 ,(2000) , 10.1007/S002620000122
A. W. Tong, B. Seamour, J. M. Lawson, G. Ordonez, S. Vukelja, W. Hyman, D. Richards, L. Stein, P. B. Maples, J. Nemunaitis, Cellular Immune Profile of Patients With Advanced Cancer Before and After Taxane Treatment American Journal of Clinical Oncology. ,vol. 23, pp. 463- 472 ,(2000) , 10.1097/00000421-200010000-00007
Richard A. Morgan, Nachimuthu Chinnasamy, Daniel Abate-Daga, Alena Gros, Paul F. Robbins, Zhili Zheng, Mark E. Dudley, Steven A. Feldman, James C. Yang, Richard M. Sherry, Giao Q. Phan, Marybeth S. Hughes, Udai S. Kammula, Akemi D. Miller, Crystal J. Hessman, Ashley A. Stewart, Nicholas P. Restifo, Martha M. Quezado, Meghna Alimchandani, Avi Z. Rosenberg, Avindra Nath, Tongguang Wang, Bibiana Bielekova, Simone C. Wuest, Nirmala Akula, Francis J. McMahon, Susanne Wilde, Barbara Mosetter, Dolores J. Schendel, Carolyn M. Laurencot, Steven A. Rosenberg, Cancer regression and neurological toxicity following anti-MAGE-A3 TCR gene therapy. Journal of Immunotherapy. ,vol. 36, pp. 133- 151 ,(2013) , 10.1097/CJI.0B013E3182829903
Matthew L. Albert, Jennifer C. Darnell, Armin Bender, Loise M. Francisco, Nina Bhardwaj, Robert B. Darnell, Tumor-specific killer cells in paraneoplastic cerebellar degeneration Nature Medicine. ,vol. 4, pp. 1321- 1324 ,(1998) , 10.1038/3315
Georgina V Long, Uwe Trefzer, Michael A Davies, Richard F Kefford, Paolo A Ascierto, Paul B Chapman, Igor Puzanov, Axel Hauschild, Caroline Robert, Alain Algazi, Laurent Mortier, Hussein Tawbi, Tabea Wilhelm, Lisa Zimmer, Julie Switzky, Suzanne Swann, Anne-Marie Martin, Mary Guckert, Vicki Goodman, Michael Streit, John M Kirkwood, Dirk Schadendorf, Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial Lancet Oncology. ,vol. 13, pp. 1087- 1095 ,(2012) , 10.1016/S1470-2045(12)70431-X