Ictal Scalp EEG in Unilateral Mesial Temporal Lobe Epilepsy

摘要: Summary: Purpose: We wished to determine the predictive significance of unilateral hippocampal atrophy and interictal spikes on localization ictal scalp EEG changes assess whether provides information that might change treatment or influence prognosis in patients with such characteristics epilepsy. Methods: analyzed seizure patterns 118 seizures 24 mesial temporal lobe epilepsy (MTLE) defined by typical clinical semiology, magnetic resonance imaging (MRI) unitemporal EEG. Two blinded electroencephalographers independently determined morphology, location, time course changes. Results: Lateralization was possible 88.4–92.0% always corresponded side spike focus MRI. Although only 30.4–33.9% were lateralized at onset, a later significant pattern emerged (12.6–13.3 s after onset) allowed lateralization 82.4–91.O% non-lateralized onset. Interobserver reliability for excellent, K-value 0.85. In most patients, either all (79.2–83.3%) >50% (8.3–16.7%) lateralized. small proportion (4.2–8.3%) 40% 1 patient, no could be electroencephalographer. The results recordings did not alter surgical approach correlate outcome. Conclusions: conclude MRI can predict high degree additional localizing this particular patient group.