Primary pulmonary lymphoma

摘要: Three distinct entities are now covered by the definition of primary pulmonary clonal lymphoid proliferation. The aim this review is to describe pathophysiological, diagnostic, prognostic and therapeutic aspects these three entities. Low-grade B-cell lymphoma most frequent form It arises from mucosa-associated tissue. usually indolent appears in a chronic alveolar opacity. prognosis excellent, but treatment controversial (simple monitoring, surgery or single-agent chemotherapy). High-grade far rarer occurs individuals with an underlying disorder (e.g. immunodeficiency). poor options depend on disorder. inclusion lymphomatoid granulomatosis lymphomas controversial. nature proliferation very rarely demonstrated extrapulmonary involvement (upper airways, skin, kidneys, central nervous system, etc.). extremely variable, some authors reporting complete remission steroids cyclophosphamide others failure combination chemotherapy.