The effects of L-carnitine L-tartrate supplementation on hormonal responses to resistance exercise and recovery.

作者: William J. Kraemer , Jeff S. Volek , Duncan N. French , Martyn R. Rubin , Matthew J. Sharman

DOI: 10.1519/1533-4287(2003)017<0455:TEOLLS>2.0.CO;2

关键词:

摘要: The purpose of this investigation was to examine the influence L-carnitine L-tartrate (LCLT) supplementation using a balanced, cross-over, placebo-controlled research design on anabolic hormone response (i.e., testosterone [T], insulin-like growth factor-I, factor-binding protein-3 [IGFBP-3], and immunofunctional immunoreactive [GHif GHir]) acute resistance exercise. Ten healthy, recreationally weight-trained men (mean +/- SD age 23.7 2.3 years, weight 78.7 8.5 kg, height 179.2 4.6 cm) volunteered were matched, after 3 weeks (2 g LCLT per day), fasting morning blood samples obtained six consecutive days (D1-D6). Subjects performed squat protocol (5 sets 15-20 repetitions) D2. During protocol, before exercise 0, 15, 30, 120, 180 minutes postexercise. After 1-week washout period, subjects consumed other supplement for 3-week same experimental repeated exact procedures. Expected exercise-induced increases in all hormones observed GHir, GHif, IGFBP-3, T. Over recovery reduced amount muscle tissue damage, which assessed via magnetic resonance imaging scans thigh. significantly (p < 0.05) increased IGFBP-3 concentrations prior at No direct effects absolute examined, but with more undamaged tissue, greater number intact receptors would be available hormonal interactions. These data support use as hypoxic lend further insights into mechanisms that may help mediate quicker recovery.

参考文章(28)
Fawzi Kadi, Adaptation of human skeletal muscle to training and anabolic steroids. Acta Physiologica Scandinavica. ,vol. 646, pp. 1- 52 ,(2000)
Christopher Barnett, David L. Costill, Mathew D. Vukovich, Kevin J. Cole, Bret H. Goodpaster, Scott W. Trappe, William J. Fink, Effect of L-carnitine supplementation on muscle and blood carnitine content and lactate accumulation during high-intensity sprint cycling. International Journal of Sport Nutrition. ,vol. 4, pp. 280- 288 ,(1994) , 10.1123/IJSN.4.3.280
M. Soop, O. Bjorkman, G. Cederblad, L. Hagenfeldt, J. Wahren, Influence of carnitine supplementation on muscle substrate and carnitine metabolism during exercise Journal of Applied Physiology. ,vol. 64, pp. 2394- 2399 ,(1988) , 10.1152/JAPPL.1988.64.6.2394
W. J. Kraemer, B. A. Aguilera, M. Terada, R. U. Newton, J. M. Lynch, G. Rosendaal, J. M. McBride, S. E. Gordon, K. Hakkinen, Responses of IGF-I to endogenous increases in growth hormone after heavy-resistance exercise Journal of Applied Physiology. ,vol. 79, pp. 1310- 1315 ,(1995) , 10.1152/JAPPL.1995.79.4.1310
GREG J. WILSON, ROBERT U. NEWTON, ARON J. MURPHY, BRENDAN J. HUMPHRIES, The optimal training load for the development of dynamic athletic performance Medicine and Science in Sports and Exercise. ,vol. 25, pp. 1279- 1286 ,(1993) , 10.1249/00005768-199311000-00013
MARTYN R. RUBIN, JEFF S. VOLEK, ANA L. GÓMEZ, NICHOLAS A. RATAMESS, DUNCAN N. FRENCH, MATTHEW J. SHARMAN, WILLIAM J. KRAEMER, Safety measures of L-carnitine L-tartrate supplementation in healthy men. Journal of Strength and Conditioning Research. ,vol. 15, pp. 486- 490 ,(2001) , 10.1519/1533-4287(2001)015<0486:SMOLCL>2.0.CO;2
Olli J. Heinonen, Carnitine and Physical Exercise Sports Medicine. ,vol. 22, pp. 109- 132 ,(1996) , 10.2165/00007256-199622020-00005
W. Kraemer, S. Gordon, S. Fleck, L. Marchitelli, R. Mello, J. Dziados, K. Friedl, E. Harman, C. Maresh, A. Fry, Endogenous anabolic hormonal and growth factor responses to heavy resistance exercise in males and females. International Journal of Sports Medicine. ,vol. 12, pp. 228- 235 ,(1991) , 10.1055/S-2007-1024673
Gary A. Dudley, Joe Czerkawski, Annette Meinrod, Garry Gillis, Angela Baldwin, Michael Scarpone, Efficacy of naproxen sodium for exercise-induced dysfunction muscle injury and soreness. Clinical Journal of Sport Medicine. ,vol. 7, pp. 3- 10 ,(1997) , 10.1097/00042752-199701000-00002
Bradley C Nindl, William J Kraemer, Wesley C Hymer, Immunofunctional vs immunoreactive growth hormone responses after resistance exercise in men and women Growth Hormone & IGF Research. ,vol. 10, pp. 99- 103 ,(2000) , 10.1054/GHIR.2000.0146