A Sapecin Homologue of Holotrichia Diomphalia: Purification, Sequencing and Determination of Disulfide Pairs

作者: So LEE , Hyun MOON , Shunichiro KAWABATA , Shoichiro KURATA , Shunji NATORI

DOI: 10.1248/BPB.18.457

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摘要: We purified and characterized a sapecin homologue, named holotricin 1, from the hemolymph of immunized larvae coleopteran insect, Holotrichia diomphalia. determined its complete amino acid sequence three disulfide pairs. Holotricin 1 consisted 43 residues showed potent antibacterial activity against gram-positive bacteria, but gram-negative bacteria was not obvious.

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