Severe vasculitic neuropathy following influenza vaccination

摘要: Current Department of Health (UK) guidelines suggest that all people aged over 65 years should receive annual influenza vaccination. There is a range adverse medical sequelae associated with this. Two serious complications are Guillain-Barre syndrome1 and systemic vasculitis.2,3 The strength association between vaccination syndrome has been questioned, little known the pathogenesis.3 Several investigators have reported close temporal vasculitis various classifications.2,3 Vasculitic peripheral neuropathy was not feature in any cases.2,3 We report case biopsy proven vasculitis, presenting as mononeuritis multiplex, following clinical picture evolved rapidly into indistinguishable from axonal syndrome. This suggests differential diagnosis for post-vaccination neuropathy, implications management. We believe this first which there an at presentation. It raises issues about aetiology pathogenesis neuropathy. A previously fit active 72 year old woman admitted after routine She gave history progressive distal arm leg …