delta-Aminolevulinate dehydrase: a new genetic polymorphism in man.

作者: G. BATTISTUZZI , R. PETRUCCI , L. SILVAGNI , F. R. URBANI , S. CAIOLA

DOI: 10.1111/J.1469-1809.1981.TB00333.X

关键词:

摘要: SUMMARY A method has been developed for the electrophoretic and quantitative analyses of human red cell δ-aminolevulinate dehydrase (ALADH). The enzyme is under control an autosomal gene, with two common codominant alleles, ALADH1 ALADH2, frequencies 0–89 Oil, respectively, in Italian population. Mean phenotypic activities are nearly identical: 52, 49 55 mlU/g Hb ALADH 1, 2-1 2 phenotypes respectively.

参考文章(7)
V. Battistini, J. J. Morrow, D. Ginsburg, G. Thompson, M. R. Moore, A. Goldberg, Erythrocyte Delta-Aminolaevulic Acid Dehydrase Activity in Anaemia British Journal of Haematology. ,vol. 20, pp. 177- 184 ,(1971) , 10.1111/J.1365-2141.1971.TB07026.X
S. Sassa, S. Granick, D.R. Bickers, R.D. Levere, A. Kappas, Studies on the inheritance of human erythrocyte delta-aminolevulinate dehydratase and uroporphyrinogen synthetase. Enzyme. ,vol. 16, pp. 326- 333 ,(1973) , 10.1159/000459397
S. Granick, D. Mauzerall, PORPHYRIN BIOSYNTHESIS IN ERYTHROCYTES Journal of Biological Chemistry. ,vol. 232, pp. 1119- 1140 ,(1958) , 10.1016/S0021-9258(19)77426-2
P M Anderson, R J Desnick, Purification and properties of delta-aminolevulinate dehydrase from human erythrocytes. Journal of Biological Chemistry. ,vol. 254, pp. 6924- 6930 ,(1979) , 10.1016/S0021-9258(18)50263-5
E.J. van Kampen, W.G. Zijlstra, Standardization of hemoglobinometry. II. The hemiglobincyanide method. Clinica Chimica Acta. ,vol. 6, pp. 538- 544 ,(1961) , 10.1016/0009-8981(61)90145-0