Erythrocyte Delta-Aminolaevulic Acid Dehydrase Activity in Anaemia
作者： V. Battistini , J. J. Morrow , D. Ginsburg , G. Thompson , M. R. Moore
DOI: 10.1111/J.1365-2141.1971.TB07026.X
关键词: Reticulocyte 、 Lead poisoning 、 Rheumatoid arthritis 、 Internal medicine 、 Close relationship 、 Vitamin B12 、 Enzyme assay 、 Enzyme 、 Cyanocobalamin 、 Medicine 、 Endocrinology 、 Immunology
摘要: Summary. A method is described for measuring the activity of enzyme δ-aminolaevulic acid dehydrase (ALA-dehydrase) in erythrocytes normal subjects and patients with macrocytic anaemia due to vitamin-B12 folic-acid deficiency, iron-deficiency anaemia, lead poisoning secondary anaemias rheumatoid arthritis carcinomatosis. A significant increase pre-treatment was found anaemias, whether a deficiency vitamin B12 or folie acid. further rise ALA-dehydrase occurred close relationship reticulocyte response, returning levels as their numbers fell. Enzyme returned 2 mth. Enzyme significantly diminished poisoning. No difference from carcinomatosis. Enzyme assay bled rabbits showed that directly related number reticulocytes present.
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