Mediastinitis in heart transplantation

作者: Shreekanth V. Karwande , Dale G. Renlund , Stephanie L. Olsen , William A. Gay , Wayne E. Richenbacher

DOI: 10.1016/0003-4975(92)90067-E

关键词:

摘要: Abstract Between March 1985 and December 1991, mediastinitis developed in 12 of 420 cardiac transplantation patients (2.8%). The mortality rate this group was 8.3% ( 1 / ). Actuarial survival (1 year, 75%; 5 years, 65%) not significantly different from that the without 88%; 75%). A higher percentage with were listed as UNOS status (50% versus 35%) had a history previous stemotomies (58% 44%). presentation typical. Computed tomographic scanning or aspiration valuable adjunct diagnosis mediastinitis. Induction immunotherapy minimal steroids perioperative period used all patients. This may contribute to patients' ability mount an appropriate effective response infection, permitting earlier diagnosis. debridement irrigation technique 8 low success 33%, whereas muscle flap 4 100% successful eliminating infection.

参考文章(26)
Menkis Ah, Pflugfelder Pw, Novick Rj, Powell Am, Kostuk Wj, Reid J, McKenzie Fn, Reid Kr, Whitby Jl, Reduced incidence of severe infection after heart transplantation with low-intensity immunosuppression. Journal of Heart and Lung Transplantation. ,vol. 10, pp. 894- 900 ,(1991)
Miller R, Burton Na, Karwande Sv, Ruder J, Treatment of mediastinitis after heart transplantation. The Journal of heart transplantation. ,vol. 5, pp. 477- ,(1986)
Cyrus Serry, Phyllis C. Bleck, Hushang Javid, James A. Hunter, Marshall D. Goldin, Giacomo A. DeLaria, Hassan Najafi, Sternal wound complications. Management and results. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 80, pp. 861- 867 ,(1980) , 10.1016/S0022-5223(19)37692-5
Lester R. Bryant, Frank C. Spencer, J. Kent Trinkle, Treatment of Median Sternotomy Infection by Mediastinal Irrigation with an Antibiotic Solution Annals of Surgery. ,vol. 169, pp. 914- 920 ,(1969) , 10.1097/00000658-196906000-00011
Peter C. Pairolero, Phillip G. Arnold, Management of Infected Median Sternotomy Wounds The Annals of Thoracic Surgery. ,vol. 42, pp. 1- 2 ,(1986) , 10.1016/S0003-4975(10)61822-X
Edward M. Gilbert, Charles W. Dewitt, Clement C. Eiswirth, Dale G. Renlund, Ronald L. Menlove, Linda A. Freedman, Colette M. Herrick, William A. Gay, Michael R. Bristow, Treatment of refractory cardiac allograft rejection with OKT3 monoclonal antibody The American Journal of Medicine. ,vol. 82, pp. 202- 206 ,(1987) , 10.1016/0002-9343(87)90056-8
Foad Nahai, Louis Morales, David K. Bone, John Bostwick, Pectoralis major muscle turnover flaps for closure of the infected sternotomy wound with preservation of form and function. Plastic and Reconstructive Surgery. ,vol. 70, pp. 471- 474 ,(1982) , 10.1097/00006534-198210000-00010
Philip L. Glick, B. Joseph Guglielmo, Robert F. Tranbaugh, Kevin Turley, Iodine Toxicity in a Patient Treated by Continuous Povidone-Iodine Mediastinal Irrigation The Annals of Thoracic Surgery. ,vol. 39, pp. 478- 480 ,(1985) , 10.1016/S0003-4975(10)61965-0
Henry W. Neale, Joel G. Kreilein, J Tracy Schreiber, Richard O. Gregory, Complete sternectomy for chronic osteomyelitis with reconstruction using a rectus abdominis myocutaneous island flap. Annals of Plastic Surgery. ,vol. 6, pp. 305- 314 ,(1981) , 10.1097/00000637-198104000-00010
Eugene A. Grossi, Alfred T. Culliford, Karl H. Krieger, David Kloth, Robert Press, F. Gregory Baumann, Frank C. Spencer, A Survey of 77 Major Infectious Complications of Median Sternotomy: A Review of 7,949 Consecutive Operative Procedures The Annals of Thoracic Surgery. ,vol. 40, pp. 214- 223 ,(1985) , 10.1016/S0003-4975(10)60030-6