Differences between CAFs and their paired NCF from adjacent colonic mucosa reveal functional heterogeneity of CAFs, providing prognostic information

作者: Mireia Berdiel-Acer , Rebeca Sanz-Pamplona , Alexandre Calon , Daniel Cuadras , Antoni Berenguer

DOI: 10.1016/J.MOLONC.2014.04.006

关键词:

摘要: … lines to a greater extent than did NCF. In vivo, CAFs were more … microarrays of CAF and paired NCF populations enabled us to … Additionally NCF already depicted an activated pattern …

参考文章(37)
Paolo Cirri, Paola Chiarugi, Cancer associated fibroblasts: the dark side of the coin American Journal of Cancer Research. ,vol. 1, pp. 482- 497 ,(2011)
Mireia Berdiel-Acer, Monika E. Bohem, Adriana López-Doriga, August Vidal, Ramon Salazar, Maria Martínez-Iniesta, Cristina Santos, Xavier Sanjuan, Alberto Villanueva, David G. Molleví, Hepatic Carcinoma-Associated Fibroblasts Promote an Adaptative Response in Colorectal Cancer Cells That Inhibit Proliferation and Apoptosis: Nonresistant Cells Die by Nonapoptotic Cell Death Neoplasia. ,vol. 13, pp. 931- 946 ,(2011) , 10.1593/NEO.11706
AF Olumi, GD Grossfeld, SW Hayward, PR Carroll, GR Cunha, P Hein, TD Tlsty, Carcinoma-associated fibroblasts stimulate tumor progression of initiated human epithelium Breast Cancer Research. ,vol. 2, pp. 5002- 5011 ,(2000) , 10.1186/BCR138
M Bauer, G Su, C Casper, R He, W Rehrauer, A Friedl, None, Heterogeneity of gene expression in stromal fibroblasts of human breast carcinomas and normal breast Oncogene. ,vol. 29, pp. 1732- 1740 ,(2010) , 10.1038/ONC.2009.463
E Louie, X F Chen, A Coomes, K Ji, S Tsirka, E I Chen, Neurotrophin-3 modulates breast cancer cells and the microenvironment to promote the growth of breast cancer brain metastasis Oncogene. ,vol. 32, pp. 4064- 4077 ,(2013) , 10.1038/ONC.2012.417
J Nemunaitis, M Nemunaitis, N Senzer, P Snitz, C Bedell, P Kumar, B Pappen, P B Maples, D Shawler, H Fakhrai, Phase II trial of Belagenpumatucel-L, a TGF-beta2 antisense gene modified allogeneic tumor vaccine in advanced non small cell lung cancer (NSCLC) patients. Cancer Gene Therapy. ,vol. 16, pp. 620- 624 ,(2009) , 10.1038/CGT.2009.15
Howard Y Chang, Jen-Tsan Chi, Sandrine Dudoit, Chanda Bondre, Matt van de Rijn, David Botstein, Patrick O Brown, None, Diversity, topographic differentiation, and positional memory in human fibroblasts Proceedings of the National Academy of Sciences of the United States of America. ,vol. 99, pp. 12877- 12882 ,(2002) , 10.1073/PNAS.162488599
Mina J Bissell, William C Hines, None, Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression Nature Medicine. ,vol. 17, pp. 320- 329 ,(2011) , 10.1038/NM.2328
R. Navab, D. Strumpf, B. Bandarchi, C.-Q. Zhu, M. Pintilie, V. R. Ramnarine, E. Ibrahimov, N. Radulovich, L. Leung, M. Barczyk, D. Panchal, C. To, J. J. Yun, S. Der, F. A. Shepherd, I. Jurisica, M.-S. Tsao, Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer Proceedings of the National Academy of Sciences of the United States of America. ,vol. 108, pp. 7160- 7165 ,(2011) , 10.1073/PNAS.1014506108
Felipe de Sousa E Melo, Selcuk Colak, Joyce Buikhuisen, Jan Koster, Kate Cameron, Joan H. de Jong, Jurriaan B. Tuynman, Pramudita R. Prasetyanti, Evelyn Fessler, Saskia P. van den Bergh, Hans Rodermond, Evelien Dekker, Chris M. van der Loos, Steven T. Pals, Marc J. van de Vijver, Rogier Versteeg, Dick J. Richel, Louis Vermeulen, Jan Paul Medema, Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients Cell Stem Cell. ,vol. 9, pp. 476- 485 ,(2011) , 10.1016/J.STEM.2011.10.008