The screening of four aminoglycosides in the selective decontamination of the digestive tract in mice.

摘要: The suppressive effect of amikacin, gentamicin, tobramycin and paromomycin on the aerobic endogenous flora colonization resistance digestive tract was tested by administering one antibiotics orally at five different dose levels. At a certain level, all suppressed Enterobacteriaceae species. Amikacin particularly effective in this respect. Low doses amikacin rapidly destroyed resistance. This only remained unaffected animals treated with that were still adequate to completely suppress We concluded study, may have future (clinical) application for selective decontamination tract. Selective can be considered an method infection prevention leukopenic patients.