Detection and Clinical Significance of COX-2 Gene SNPs in Gastric Cancer

作者: Xingre Lu , Fengyu Chen , Xiaowen Liu , Diao Yuan , Yunju Zi

DOI: 10.1007/S12013-014-0465-8

关键词:

摘要: Gastric cancer has high morbidity and mortality. Identification of patients with gastric risk at early stage will improve patient prognosis. In this study, we examined two single nucleotide polymorphism (SNP) sites COX-2 gene in explored the effect SNPs on cancer. We found that COX-2-1195G/A COX-2-8473T/C are correlated occurrence cancer, variants A C liable to have Our study provides a potential method for screening susceptible population early-stage intervention patients.

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