Adolescent Neurobehavioral Characteristics, Alcohol Sensitivities, and Intake: Setting the Stage for Alcohol Use Disorders?

作者: Linda Patia Spear

DOI: 10.1111/J.1750-8606.2011.00182.X

关键词:

摘要: The transition to adolescence is characterized by rapid biological transformations that include not only the hormonal and physiological changes of puberty but also dramatic in brain as well. Similar neural are associated with from immaturity maturity across a variety mammalian species, along common adolescent-typical behavioral characteristics. Among systems undergoing alterations during those modulate sensitivity alcohol effects, potentially increasing propensity for relatively high levels adolescent use, which turn may set stage later use disorders. This article reviews research on sensitivities suggests possible implications these findings frequent initiation intake seen at this age.

参考文章(91)
Susan F. Tapert, Alecia D. Schweinsburg, The Human Adolescent Brain and Alcohol Use Disorders Recent developments in alcoholism : an official publication of the American Medical Society on Alcoholism, the Research Society on Alcoholism, and the National Council on Alcoholism. ,vol. 17, pp. 177- 197 ,(2005) , 10.1007/0-306-48626-1_9
Pasko Rakic, Jean-Pierre Bourgeois, Patricia S. Goldman-Rakic, Synaptic development of the cerebral cortex: implications for learning, memory, and mental illness Progress in Brain Research. ,vol. 102, pp. 227- 243 ,(1994) , 10.1016/S0079-6123(08)60543-9
Amy R. Brooks-Kayal, Melissa D. Shumate, Hong Jin, Tatiana Y. Rikhter, Mary Ellen Kelly, Douglas A. Coulter, γ-Aminobutyric acidA receptor subunit expression predicts functional changes in hippocampal dentate granule cells during postnatal development Journal of Neurochemistry. ,vol. 77, pp. 1266- 1278 ,(2001) , 10.1046/J.1471-4159.2001.00329.X
Robert A. Zucker, Mary M. Heitzeg, Joel T. Nigg, Parsing the Undercontrol/Disinhibition Pathway to Substance Use Disorders: A Multilevel Developmental Problem Child Development Perspectives. ,vol. 5, pp. 248- 255 ,(2011) , 10.1111/J.1750-8606.2011.00172.X
Esa L. Osterberg, Salme K. Ahlstrom, International Perspectives on Adolescent and Young Adult Drinking Alcohol Research & Health. ,vol. 28, pp. 258- ,(2004)
Danielle M. Dick, Developmental Changes in Genetic Influences on Alcohol Use and Dependence Child Development Perspectives. ,vol. 5, pp. 223- 230 ,(2011) , 10.1111/J.1750-8606.2011.00207.X
Kenneth H. Beck, Dennis L. Thombs, Terry G. Summons, The social context of drinking scales: Construct validation and relationship to indicants of abuse in an adolescent population Addictive Behaviors. ,vol. 18, pp. 159- 169 ,(1993) , 10.1016/0306-4603(93)90046-C