Serum adenosine deaminase levels in patients with psoriasis: a prospective case-control study

摘要: Adenosine deaminase (ADA) activity is a nonspecific marker of T cell activation. activation thought to play an important role in the pathogenesis psoriasis. Our purpose was assess significance serum ADA psoriasis and its relevance disease activity. determined with enzymatic method 25 patients 15 healthy subjects. These measurements were repeated for 10 after either PUVA or cyclosporin A treatments. Disease estimated by PASI scoring system. Serum level significantly elevated compared subjects (p<0.05). There significant decrease levels treatment pretreatment values same no correlation between scores. results support evidence that involved may be valuable assessment