Comparison of Electron Beam Computed Tomography With Intracoronary Ultrasound and Coronary Angiography for Detection of Coronary Atherosclerosis

摘要: Abstract Objectives. This analysis compared the results of electron beam computed tomography (EBCT) with those coronary angiography and intracoronary ultrasound (ICUS) for in vivo detection atherosclerotic plaques. Background. EBCT is a new imaging modality identification calcifications. Coronary depicts advanced changes morphology, whereas ICUS an established diagnostic tool that detects early stages artery disease. Methods. In 57 patients (54 ± 9 years old), 267 segments were analyzed (3-mm slices, acquisition time 100 ms, threshold definition calcification at 130 Hounsfield units area ≥1 mm2, Agatston calcium score), ICUS. The was based on number extent calcifications EBCT, lumen reduction plaque formation without signs Results. Compared angiography, yielded sensitivity 66%, specificity 78%, positive predictive value 39% negative 91%. ICUS, overall 88% accuracy 81%. For plaques calcifications, 97% 47%, 80% 75% 82% 69%, respectively. Conclusions. correlation between demonstrates noninvasive method helps to visualize process by localization quantification calcified high accuracy. Plaques can be detected but lower equivalent specificity. (J Am Coll Cardiol 1997;30:57–64)