Particulate air pollution and preeclampsia: a source-based analysis

作者: Payam Dadvand , Bart Ostro , Fulvio Amato , Francesc Figueras , María-Cruz Minguillón

DOI: 10.1136/OEMED-2013-101693

关键词:

摘要: Objectives To investigate the association between preeclampsia and maternal exposure to ambient particulate matter (PM) with aerodynamic diameter less than 10 μm (PM 10 ) 2.5 μm 2.5 mass sources. Methods Our analysis was based on a hospital cohort of pregnant women (N=3182) residing in Barcelona, Spain, during 2003–2005. Positive matrix factorisation source apportionment (PMF2) used identify sources PM samples obtained by an urban background monitor, resulting detection eight We further combined traffic-related (brake dust, vehicle exhaust secondary nitrate/organics) generate indicator traffic Logistic regression models were developed estimate each separately entire pregnancy trimester one, adjusted for relevant covariates. Results For pregnancy, we found 44% (95% CI 7% 94%) 80% 4% 211%) increase risk associated one IQR brake dust sources, respectively. These findings remained consistent after alternative method (Multilinear Engine (ME2)) used. The results also inconclusive. Conclusions: Risk

参考文章(55)
Thomas Kennedy, Andrew J. Ghio, William Reed, James Samet, John Zagorski, Jacqueline Quay, Jacqueline Carter, Lisa Dailey, John R. Hoidal, Robert B. Devlin, Copper-dependent Inflammation and Nuclear Factor- κ B Activation by Particulate Air Pollution American Journal of Respiratory Cell and Molecular Biology. ,vol. 19, pp. 366- 378 ,(1998) , 10.1165/AJRCMB.19.3.3042
Payam Dadvand, Xavier Basagaña, Francesc Figueras, Elmira Amoly, Aurelio Tobias, Audrey de Nazelle, Xavier Querol, Jordi Sunyer, Mark J. Nieuwenhuijsen, Saharan dust episodes and pregnancy Journal of Environmental Monitoring. ,vol. 13, pp. 3222- 3228 ,(2011) , 10.1039/C1EM10579E
Jun Wu, Cizao Ren, Ralph J. Delfino, Judith Chung, Michelle Wilhelm, Beate Ritz, Association between local traffic-generated air pollution and preeclampsia and preterm delivery in the south coast air basin of California. Environmental Health Perspectives. ,vol. 117, pp. 1773- 1779 ,(2009) , 10.1289/EHP.0800334
F. Figueras, E. Meler, A. Iraola, E. Eixarch, O. Coll, J. Figueras, A. Francis, E. Gratacos, J. Gardosi, Customized birthweight standards for a Spanish population. European Journal of Obstetrics & Gynecology and Reproductive Biology. ,vol. 136, pp. 20- 24 ,(2008) , 10.1016/J.EJOGRB.2006.12.015
Kenneth J. Rothman, No adjustments are needed for multiple comparisons. Epidemiology. ,vol. 1, pp. 43- 46 ,(1990) , 10.1097/00001648-199001000-00010
Therese F Mar, Kazuhiko Ito, Jane Q Koenig, Timothy V Larson, Delbert J Eatough, Ronald C Henry, Eugene Kim, Francine Laden, Ramona Lall, Lucas Neas, Matthias Stölzel, Pentti Paatero, Philip K Hopke, George D Thurston, PM source apportionment and health effects. 3. Investigation of inter-method variations in associations between estimated source contributions of PM2.5 and daily mortality in Phoenix, AZ. Journal of Exposure Science and Environmental Epidemiology. ,vol. 16, pp. 311- 320 ,(2006) , 10.1038/SJ.JEA.7500465
Babbette LaMarca, IL-6-induced pathophysiology during pre-eclampsia: potential therapeutic role for magnesium sulfate? International Journal of Interferon, Cytokine and Mediator Research. ,vol. 2011, pp. 59- 64 ,(2011) , 10.2147/IJICMR.S16320
Jeremy A. Sarnat, Amit Marmur, Mitchel Klein, Eugene Kim, Armistead G. Russell, Stefanie E. Sarnat, James A. Mulholland, Philip K. Hopke, Paige E. Tolbert, Fine particle sources and cardiorespiratory morbidity: an application of chemical mass balance and factor analytical source-apportionment methods. Environmental Health Perspectives. ,vol. 116, pp. 459- 466 ,(2008) , 10.1289/EHP.10873
Susanne Becker, Lisa A. Dailey, Joleen M. Soukup, Steven C. Grambow, Robert B. Devlin, Yuh-Chin T. Huang, Seasonal variations in air pollution particle-induced inflammatory mediator release and oxidative stress. Environmental Health Perspectives. ,vol. 113, pp. 1032- 1038 ,(2005) , 10.1289/EHP.7996
Philip K Hopke, Kazuhiko Ito, Therese Mar, William F Christensen, Delbert J Eatough, Ronald C Henry, Eugene Kim, Francine Laden, Ramona Lall, Timothy V Larson, Hao Liu, Lucas Neas, Joseph Pinto, Matthias Stölzel, Helen Suh, Pentti Paatero, George D Thurston, PM source apportionment and health effects: 1. Intercomparison of source apportionment results. Journal of Exposure Science and Environmental Epidemiology. ,vol. 16, pp. 275- 286 ,(2006) , 10.1038/SJ.JEA.7500458