Cardiac morphology and function reference values derived from a large subset of healthy young Caucasian adults by magnetic resonance imaging.

摘要: Aims Assessment of cardiac anatomy and function by cardiovascular magnetic resonance (CMR) is accurate reproducible commonly performed to clarify borderline results obtained other techniques. Normal reference values are lacking in a large sample young healthy adults. As CMR increasingly solicited discriminate normality from equivocal disease this population, we sought determine reliable values. Methods A 434 Caucasian adults aged 26 ± 4 years (45% male) without or risk factors (including obesity smoking) underwent CMR. Blood pressure, electrocardiogram, plasma markers (lipid profile, fasting glucose, troponin, Nt-pro-BNP) were within normal limits typical low-cardiometabolic-risk profile. End-diastolic (ED), end-systolic (ES), stroke volumes greater men for left right atria ventricles. Left ventricular (LV) mass was higher men. ED wall thickness all segments men, whereas ES thickening (segmental function) similar both genders. After normalization body surface area, gender differences remained. lower, atrial older individuals. In contrast, LV not associated with age. Conclusion This the first database ranges functions, volumes, women devoid factors. These data will contribute improving accuracy interpretation clinical research applications.