Gender differences and normal left ventricular anatomy in an adult population free of hypertension ☆: A cardiovascular magnetic resonance study of the Framingham Heart Study Offspring cohort

摘要: Abstract Objectives We sought to derive gender-specific cardiovascular magnetic resonance (CMR) reference values for normative left ventricular (LV) anatomy and function in a healthy adult population of clinically relevant age. Background Cardiovascular imaging is increasingly applied the clinical setting, but age-relevant, are currently unavailable. Methods A representative sample 318 Framingham Heart Study (FHS) Offspring participants free overt disease underwent CMR examination determine LV end-diastolic end-systolic volume (EDV ESV, respectively), mass, ejection fraction (EF) linear dimensions (wall thickness, cavity length). Subjects with history hypertension or those systolic blood pressure ≥140 mm Hg diastolic ≥90 at any FHS cycle were excluded, leaving 142 subjects (63 men, 79 women; age 57 ± 9 years). Results All volumetric (EDV, mass) unidimensional measures significantly greater (p Conclusions volumes, mass differ according gender body size. This study provides normal values, uniquely derived from population-based persons hypertension. These data may serve as identify pathology population.