Lipidomics in Breast Cancer

摘要: The prevalence of breast cancer within industrialized populations and the accessibility tissue for research have meant that genomic, transcriptomic, proteomic studies often focused on cancer. This has led to major advances in understanding this disease findings been translated many other types Like common cancers, shows a lipogenic phenotype, meaning significant quantities lipids are synthesized stored cells. As importance phenotype is becoming better appreciated, beginning focus upon how lipogenesis regulated critical genes pathways involved. Lipidomic also begun characterize lipid profiles cells tissues study biological consequences these altered profiles. chapter will provide an overview biology human cancer, focusing our current lipogenesis, contributes tumor formation progression, what understood its molecular basis, techniques lipidomics be applied disease.