Adjuvants and delivery systems in veterinary vaccinology: current state and future developments

作者: Peter M. H. Heegaard , Laurence Dedieu , Nicholas Johnson , Marie-Frédérique Le Potier , Michael Mockey

DOI: 10.1007/S00705-010-0863-1

关键词:

摘要: Modern adjuvants should induce strong and balanced immune responses, it is often desirable to specific types of immunity. As an example, efficient Th1-immunity-inducing are highly in demand. Such promote good cell-mediated immunity against subunit vaccines that have low immunogenicity themselves. The development such may take advantage the increased knowledge molecular mechanisms factors controlling these responses. However, details relatively scarce for species other than humans laboratory rodents, addition, there special considerations pertaining use veterinary animals, as production companion animals. With a focus on this review highlights number approaches being pursued, including cytokines, CpG oligonucleotides, microparticles liposomes.

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