作者: W. P. Santamore , M. Constantinescu , B. M. Minczak , C. E. Hock , L. Papa
DOI: 10.1007/BF02005828
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摘要: The influences of presure and volume changes in one ventricle on the other may be determined from relative compliances ventricular free walls interventricular septum. If this is correct, then disease states which alter regional should influence diastolic mechanical coupling between ventricles. To examine hypothesis, hearts 15 canine dogs were removed placed cool cardioplegic solution. Balloons inserted into each right left pressure (ΔPr, ΔPl) (ΔVr, ΔVl) caused by changing recorded. Acute wall (N=5), septal (N=5) induced glutaraldehyde injections. After injecting coronary artery, ΔPl/ΔVr, ΔVl/ΔVr, ΔPr/ΔPl, ΔPr/ΔVl increased significantly (P<0.05). artery injection, transfer ventricles was depressed. ΔPl/ΔPr, ΔPr/ΔVl, ΔVr/ΔVl Thus, selective alterations occurred following ventricular, septal, compliances. Such important diseases primarily affect side heart.