Different prognostic significance of right and Left ventricular diastolic dysfunction in Heart failure

摘要: Background: Left (LV) and right (RV) ventricular diastolic dysfunction is common in heart failure but the prognostic value of RV not known. Hypothesis: As a follow-up to previously undertaken study, this study was carried out investigate whether LV affect prognosis differently and, addition, changes filling patterns over time correlate with clinical outcome. Methods: We studied cohort 105 patients (mean age 62.7± 1.3 years, 66% male) (ejection fraction < 50%) by Doppler echocardiography both LV. Results: An restrictive pattern (RFP) present 48% when compared non-RFP subgroups, it associated poorer systolic function, higher New York Heart Association functional class, cardiac mortality at 1 year (all p 0.001). The coexistence an LV-RFP poor function 25%) markedly decreased 1-year survival that significant other subgroups (p = In contrast, occurred 21% factor for either alone or combination dysfunction, predicted nonfatal hospital admissions unstable angina 0.016). Conclusion: powerful predictor prognosis, especially combined low ejection fraction, did appear be independent subsequent mortality.