Molecular mechanism of Aurora A kinase autophosphorylation and its allosteric activation by TPX2

作者: Adelajda Zorba , Vanessa Buosi , Steffen Kutter , Nadja Kern , Francesco Pontiggia

DOI: 10.7554/ELIFE.02667

关键词:

摘要: We elucidate the molecular mechanisms of two distinct activation strategies (autophosphorylation and TPX2-mediated activation) in human Aurora A kinase. Classic …

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