Failure of somatostatin or an analog to promote closure of end pancreatic fistulae.

摘要: Somatostatin has been reported to promote closure of pancreatic fistulae, but use the analog SMS 201-995 (Sandoz, Inc.) not previously publishede We used this treat two patients with end fistulae refractory conventional therapy. One patient had disruption a pancreaticojejunostomy after pancreaticoduodenectomy and other acute necrotizing gallstone pancreatitis duct in tail. (100-150 μg/d) abruptly decreased fistula output by 50% both further increases dosage no effect on output. Neither healed 3–4 wk Treatment somatostatin or its analogs alone will lead complicated factors such as distal obstruction, infection, foreign body. may lateral simplify management high fistulae.