Does Menopause Increase the Risk of Coronary Heart Disease

摘要: It has been a constant finding for more than century that there is marked sex difference in risk of coronary heart disease (CHD). There however little understanding explaining the basis this difference. The often-held assumption ovarian estrogen as principal endogenous cardioprotective factor to explain based on decline ratio male-to-female deaths from CHD begins fifth decade. This male/female thought be related an increase mortality among women following menopause. If were true rate female rates should visible age at which menopause usually occurs. chapter reviews both epidemiologic studies, had its objective find evidence increase, and mechanistic studies.