The Effect of Palmityl Coenzyme A on Glucose 6-Phosphate Dehydrogenase and Other Enzymes

摘要: Abstract Palmityl coenzyme A was found to inhibit and inactivate both purified yeast crude rat liver glucose 6-phosphate dehydrogenase. The enzyme inhibited 50% at a concentration of 0.0031 mm. inhibition strictly competitive reversible with respect the mixed type TPN. Bovine serum albumin hydroxylamine prevented reversed inhibition, but no restoration activity possible once became inactivated. Of group 12 other enzymes diverse metabolic function which were tested, 7 or inactivated, both, by very low concentrations acyl ester. Glutamic dehydrogenase be most sensitive as occurred 3 x 10-4 In view widespread palmityl esters, physiological role these esters regulators certain pathways must viewed reservation.