作者: Peter Schneede , Reza S. Malek
关键词:
摘要: Summary Evidently humans and dermatotropic human papillomaviruses have co-existed since the beginning of humanity (1). Today, sensitive laboratory detection techniques show that are currently most frequent causative organisms sexually transmissible viral diseases (2). Therefore HPV infections genitals very widespread in active population throughout world. The sexual transmissibility condylomata acuminata was described for first time antiquity, these genital warts now attributabled to certain genotypes. However, not only cosmetically unattractive skin but also squamous epithelial carcinomas both sexes may be caused by papillomavirus infections. Indeed, interdisciplinary research interest focused on when oncogenic potential individual genotypes discovered, during past 25 years (3). Especially gynaecology, pathogenetic connection with one women, cervical carcinoma, is evident undisputed. But has been found dermatological as well urological gynaecological tumours. Squamous penis particular associated same carcinomas. high prevalence population, coupled turned into an extremely controversial topic health policy. Current employed strategies concern diagnosis treatment prophylaxis Lately, promising results prophylactic vaccination trials published. A placebo-controlled study a HPV-16 vaccine concluded immunizing HPV-16-negative women could possibly reduce incidence cancer (4). target current programs. similarly correlation penile carcinoma good candidate future therapeutic (5). Human worldwide prevalent all economic classes multitude medical disciplines become increasingly engaged research. many its types agents infectious such they demonstrate potential. following original papers dealing different clinical aspects lesions dermatology, gynaecology urology. In programs will hopefully contribute elimination infection papillomaviruses. However until then, laser stay therapy choice