作者: E. J. Vollaard , M. M. Jankowiak , N. F. Muller , H. A. L. Clasener
DOI: 10.1007/BF01959465
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摘要: The influence of clindamycin, dicloxacillin, minocycline and norfloxacin on the faecal concentration urobilinogen was investigated. studied drugs were administered orally in standard dosage for six days to groups volunteers. A decrease following administration clindamycin (P<0.01) dicloxacillin (P<0.05) found. possible predictive value a level as an indicator impairment microbial colonization resistance risk failure oral anticonceptive treatment is discussed. It suggested that should not be combined with unless more specific investigations have excluded interaction these oestrogen metabolism bowel.