Unfolded protein response in plants: one master, many questions.

作者: Cristina Ruberti , Sang-Jin Kim , Giovanni Stefano , Federica Brandizzi

DOI: 10.1016/J.PBI.2015.05.016

关键词:

摘要: To overcome endoplasmic reticulum (ER) stress, ER-localized stress sensors actuate distinct downstream organelle-nucleus signaling pathways to invoke a cytoprotective response, known as the unfolded protein response (UPR). Compared yeast and metazoans, plant UPR studies are more recent but nevertheless fascinating. Here we discuss discoveries in UPR, highlight conserved unique features of well critical yet-open questions whose answers will likely make significant contributions understanding ER management.

参考文章(55)
Shimpei Hayashi, Yuhya Wakasa, Hideyuki Takahashi, Taiji Kawakatsu, Fumio Takaiwa, Signal transduction by IRE1-mediated splicing of bZIP50 and other stress sensors in the endoplasmic reticulum stress response of rice. Plant Journal. ,vol. 69, pp. 946- 956 ,(2012) , 10.1111/J.1365-313X.2011.04844.X
Le Sun, Shuang-Shuang Zhang, Sun-Jie Lu, Jian-Xiang Liu, Site-1 protease cleavage site is important for the ER stress-induced activation of membrane-associated transcription factor bZIP28 in Arabidopsis Science China Life Sciences. ,vol. 58, pp. 270- 275 ,(2015) , 10.1007/S11427-015-4807-6
Hiderou Yoshida, Toshie Matsui, Akira Yamamoto, Tetsuya Okada, Kazutoshi Mori, XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor Cell. ,vol. 107, pp. 881- 891 ,(2001) , 10.1016/S0092-8674(01)00611-0
Yani Chen, Federica Brandizzi, IRE1: ER stress sensor and cell fate executor Trends in Cell Biology. ,vol. 23, pp. 547- 555 ,(2013) , 10.1016/J.TCB.2013.06.005
Shimpei Hayashi, Yuhya Wakasa, Fumio Takaiwa, Functional integration between defence and IRE1-mediated ER stress response in rice Scientific Reports. ,vol. 2, pp. 670- 670 ,(2012) , 10.1038/SREP00670
Chunhua Zhang, Simeon O. Kotchoni, A. Lacey Samuels, Daniel B. Szymanski, SPIKE1 signals originate from and assemble specialized domains of the endoplasmic reticulum Current Biology. ,vol. 20, pp. 2144- 2149 ,(2010) , 10.1016/J.CUB.2010.11.016
Jingshi Shen, Xi Chen, Linda Hendershot, Ron Prywes, ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals. Developmental Cell. ,vol. 3, pp. 99- 111 ,(2002) , 10.1016/S1534-5807(02)00203-4
Yanjie Li, Sabrina Humbert, Stephen H Howell, ZmbZIP60 mRNA is spliced in maize in response to ER stress BMC Research Notes. ,vol. 5, pp. 144- 144 ,(2012) , 10.1186/1756-0500-5-144
Heather P Harding, Yuhong Zhang, Anne Bertolotti, Huiqing Zeng, David Ron, Perk Is Essential for Translational Regulation and Cell Survival during the Unfolded Protein Response Molecular Cell. ,vol. 5, pp. 897- 904 ,(2000) , 10.1016/S1097-2765(00)80330-5