Polypeptides, polynucleotides and compositions for use in the treatment of latent tuberculosis

作者: James Brown , Dennis Murphy , Pascal Mettens

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摘要: An isolated polypeptide comprising: (i) an Rv3616c protein sequence selected from SEQ ID NO: 1 and 3-7; (Ii) a variant of 3-7, said having at least 90% identity therewith; or (iii) immunogenic fragment sequence, being 29-126, 127, 128, 130, 131-133, 135, 143-148 150-156; for use in the treatment latent tuberculosis.

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