作者: Carina Vingsbo Lundberg , Peter Andersen , Truc Thi Kim Than Hoang , Jes Dietrich
DOI:
关键词: Virology 、 Tuberculosis 、 Biology 、 Latent tuberculosis 、 Microbiology 、 Mycobacterium tuberculosis 、 Gene
摘要: The present invention discloses a vaccine or immunogenic composition that can be administred to latently infected individuals prevent reactivation of latent tuberculosis infection caused by species the complex microorganisms (Mycobacterium tuberculosis., M.bovis, M.africanum), is base on number M. derived proteins and protein fragments which are constitutively expressed in different stages infection. directed use these polypeptides, immunologically active thereof genes encoding them for immunological compositions such as vaccines.