Mtb-c vaccine against asthma
作者： Riera Isabel Amat , Iglesias Pere Joan Cardona , Moreno Blanca Reyes , Fabregat Maria Mercè Amat
DOI:
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摘要: The invention relates to an agent for the treatment or prevention of allergic condition, such as asthma, in a mammal. comprises fragments Mycobacterium tuberculosis-complex (MTB-C) strain. These particular may be from virulent MTB-C strain and/or form liposome composition. include further components, liposome-forming proteins A response that treated by is asthma. pharmaceutical composition comprising also provided. Administration described herein significantly attenuates airway hyperresponsiveness, eosinophilia and lymphocytosis airways sensitized animals. effectiveness exceeds on all evaluated parameters commercial vaccine BCG Danish 1331 Strain.
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