A family with type 2M VWD with normal VWF:RCo but reduced VWF:CB and a M1761K mutation in the A3 domain.

J Evan Sadler, A revised classification of von Willebrand disease. For the Subcommittee on von Willebrand Factor of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Thrombosis and Haemostasis. ,vol. 71, pp. 520- 525 ,(1994) , 10.1055/S-0038-1642471

V. H. FLOOD, C. A. LEDERMAN, J. S. WREN, P. A. CHRISTOPHERSON, K. D. FRIEDMAN, R. G. HOFFMANN, R. R. MONTGOMERY, Absent collagen binding in a VWF A3 domain mutant: utility of the VWF:CB in diagnosis of VWD Journal of Thrombosis and Haemostasis. ,vol. 8, pp. 1431- 1433 ,(2010) , 10.1111/J.1538-7836.2010.03869.X

Jean-Maurice Lavergne, Irène Juhan-Vague, Bernadette Obert, Ghislaine Cherel, Dominique Meyer, Jean-Pierre Girma, Anne-Sophie Ribba, Irmine Loisel, Ser968Thr mutation within the A3 domain of von Willebrand factor (VWF) in two related patients leads to a defective binding of VWF to collagen. Thrombosis and Haemostasis. ,vol. 86, pp. 848- 854 ,(2001) , 10.1055/S-0037-1616142

J. E. SADLER, U. BUDDE, J. C. J. EIKENBOOM, E. J. FAVALORO, F. G. H. HILL, L. HOLMBERG, J. INGERSLEV, C. A. LEE, D. LILLICRAP, P. M. MANNUCCI, C. MAZURIER, D. MEYER, W. L. NICHOLS, M. NISHINO, I. R. PEAKE, F. RODEGHIERO, R. SCHNEPPENHEIM, Z. M. RUGGERI, A. SRIVASTAVA, R. R. MONTGOMERY, A. B. FEDERICI, , Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor Journal of Thrombosis and Haemostasis. ,vol. 4, pp. 2103- 2114 ,(2006) , 10.1111/J.1538-7836.2006.02146.X

Anne F. Riddell, Keith Gomez, Carolyn M. Millar, Gillian Mellars, Saher Gill, Simon A. Brown, Megan Sutherland, Mike A. Laffan, Thomas A. J. McKinnon, Characterization of W1745C and S1783A: 2 novel mutations causing defective collagen binding in the A3 domain of von Willebrand factor. Blood. ,vol. 114, pp. 3489- 3496 ,(2009) , 10.1182/BLOOD-2008-10-184317

A. TOSETTO, F. RODEGHIERO, G. CASTAMAN, A. GOODEVE, A. B. FEDERICI, J. BATLLE, D. MEYER, E. FRESSINAUD, C. MAZURIER, J. GOUDEMAND, J. EIKENBOOM, R. SCHNEPPENHEIM, U. BUDDE, J. INGERSLEV, Z. VORLOVA, D. HABART, L. HOLMBERG, S. LETHAGEN, J. PASI, F. HILL, I. PEAKE, A quantitative analysis of bleeding symptoms in type 1 von Willebrand disease: results from a multicenter European study (MCMDM-1 VWD). Journal of Thrombosis and Haemostasis. ,vol. 4, pp. 766- 773 ,(2006) , 10.1111/J.1538-7836.2006.01847.X