Sleeptime diet and bone health

摘要: Osteoporosis is a multifactorial bone disease with loss of mineral and structure, which predominantly prevalent in aged women after menopause. Due to increasing life expectancy, osteoporosis becoming more important. It should be aimed develop preventive strategies against loss, are feasible, cost-effective well-accepted by the public. Bone turnover orchestrated sophisticated hormonal interplay parathyroid hormone, calcitonin vitamin D as their main regulators. Other mediators melatonin GLP-2. underlies circadian rhythm partly mediated cyclical intakes meals or nutrients, calcium particular. Calcium substrate formation but also regulator many biological processes. In general long-term compliance consumption foods higher than taking tablets. Nevertheless, habitual diets contain too little calcium. Dietary this deficit involve advice increase rich fortified foods, that enhancers absorption. Beyond time-targeted ‘bone drink snack’ fulfils these prerequisites, may maximize sparing effect. We have tested hypothesis clinical study postmenopausal who consumed calcium-rich functional milk at bedtime. observed stimulation utilisation reduction nocturnal resorption approach dietary intervention.