Pancreatic Stellate Cells (PSCs) express Cyclooxygenase-2 (COX-2) and pancreatic cancer stimulates COX-2 in PSCs
作者： Seiya Yoshida , Michael Ujiki , Xian-Zhong Ding , Carolyn Pelham , Mark S Talamonti
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摘要: Background Cyclooxygenase 2 (COX-2), the inducible form of prostaglandin G/H synthase, is associated with several human cancers including pancreatic adenocarcinoma. Pancreatic stellate cells (PSCs) play a central role in intense desmoplasia that surrounds The present study examined COX-2 expression PSCs. PSCs isolated from normal rats, were cultured and exposed to conditioned medium (CM) cell line, PANC-1.
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