Parenteral sulphadoxine-pyrimethamine (Fansidar): an effective and safe but under-used method of anti-malarial treatment.
作者： L.A. Salako , Risquat A. Adio , A. Sowunmi , O. Walker
DOI: 10.1016/0035-9203(90)90131-W
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摘要: Abstract One hundred and eighteen patients with acute falciparum malaria were randomized into treatment either intramuscular or oral sulfadoxine-pyrimethamine (Fansidar®, Roche) the results compared those from 68 treated in parallel chloroquine. Parasitological cure rate was 97% sulfadoxine-pyrimethamine, 95% injection, only 63% The time for disappearance of parasitaemia sensitive cases same shorter than Side effects occurred 3 8 tablets 13 showed that is as effective as, probably better tolerated than, drug. Increasing failure response to chloroquine Nigeria also demonstrated.
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