A comparative study of parenteral chloroquine, quinine and pyrimethamine-sulfadoxine in the treatment of Gambian children with complicated, non-cerebral malaria.
作者： B. Giadom , G. E. De Veer , M. Boele Van Hensbroek , P. T. Corrah , S. Jaffar
DOI: 10.1080/02724936.1996.11747809
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摘要: SummaryNinety-two children with complicated, but not cerebral, Plasmodium falciparum malaria, aged 1–9 years, were recruited between August 1992 and December 1994 to an open, randomized trial of parenteral chloroquine (28), pyrimethamine-sulfadoxine (P-S) (36) quinine (28). The median fever clearance time was shorter for (27 hours) than (42 or P-S (36 (p = 0.02 p 0.06, respectively). parasite times similar P-S, significantly compared (54 hours vs 66 < 0.007) 0.001). However, three who received required a change treatment because clinical failure their initial treatment. Four died, one in the group, group two group. Despite high level resistance community, t...
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