Effects on eye movements of a GABA agonist and antagonist injected into monkey superior colliculus
作者： Okihide Hikosaka , Robert H. Wurtz
DOI: 10.1016/0006-8993(83)90586-3
关键词:
摘要: Injection of muscimol, a GABA agonist, into the superior colliculus awake monkeys produces saccades to visual targets in movement field cells near injection site that have longer latency and shortened amplitude. Bicuculline, antagonist, leads irrepressible towards field. These results are consistent with tonic inhibition by substantia nigra on mediated which is reduced at time saccade initiation.
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RM Beckstead, SB Edwards, A Frankfurter, A comparison of the intranigral distribution of nigrotectal neurons labeled with horseradish peroxidase in the monkey, cat, and rat The Journal of Neuroscience. ,vol. 1, pp. 121- 125 ,(1981) , 10.1523/JNEUROSCI.01-02-00121.1981
O. Hikosaka, R. H. Wurtz, Visual and oculomotor functions of monkey substantia nigra pars reticulata. III. Memory-contingent visual and saccade responses Journal of Neurophysiology. ,vol. 49, pp. 1268- 1284 ,(1983) , 10.1152/JN.1983.49.5.1268
P. H. Schiller, S. D. True, J. L. Conway, Deficits in eye movements following frontal eye-field and superior colliculus ablations Journal of Neurophysiology. ,vol. 44, pp. 1175- 1189 ,(1980) , 10.1152/JN.1980.44.6.1175
O. Hikosaka, R. H. Wurtz, Visual and oculomotor functions of monkey substantia nigra pars reticulata. IV. Relation of substantia nigra to superior colliculus Journal of Neurophysiology. ,vol. 49, pp. 1285- 1301 ,(1983) , 10.1152/JN.1983.49.5.1285
C. W. Mohler, R. H. Wurtz, Role of striate cortex and superior colliculus in visual guidance of saccadic eye movements in monkeys. Journal of Neurophysiology. ,vol. 40, pp. 74- 94 ,(1977) , 10.1152/JN.1977.40.1.74
S.R. Vincent, T. Hattori, E.G. McGeer, The nigrotectal projection: a biochemical and ultrastructural characterization. Brain Research. ,vol. 151, pp. 159- 164 ,(1978) , 10.1016/0006-8993(78)90959-9
G. Chevalier, J.M. Deniau, A.M. Thierry, J. Feger, The nigro-tectal pathway. An electrophysiological reinvestigation in the rat Brain Research. ,vol. 213, pp. 253- 263 ,(1981) , 10.1016/0006-8993(81)90232-8
G.R. Leichnetz, R.F. Spencer, S.G.P. Hardy, J. Astruc, The prefrontal corticotectal projection in the monkey; An anterograde and retrograde horseradish peroxidase study Neuroscience. ,vol. 6, pp. 1023- 1041 ,(1981) , 10.1016/0306-4522(81)90068-3
G. Chevalier, A.M. Thierry, T. Shibazaki, J. Féger, Evidence for a GABAergic inhibitory nigrotectal pathway in the rat Neuroscience Letters. ,vol. 21, pp. 67- 70 ,(1981) , 10.1016/0304-3940(81)90059-8
Ann M. Graybiel, Organization of the nigrotectal connection: an experimental tracer study in the cat Brain Research. ,vol. 143, pp. 339- 348 ,(1978) , 10.1016/0006-8993(78)90573-5