Importance of left atrial appendage flow as a predictor of thromboembolic events in patients with atrial fibrillation

摘要: Aim The purpose of this study was to investigate the role transoesophageal echocardiography in predicting subsequent thromboembolic events patients with atrial fibrillation. Methods and Transoesophageal performed 88 documented paroxysmal (n=53) or chronic fibrillation (n=35) assess morphological functional predictors events. Prospective selection from non-valvular who had undergone because previous thromboembolism (n=30); prior electrical cardioversion (n=31); for other reasons (n=27). All were followed up 1 year. Results During period follow-up new occurred 18 (20%/year); 16 these a stroke two peripheral embolism. Univariate analysis revealed that (P<0·005; odds ratio 5·3 [CI 1·9, 12·1]), history hypertension (P<0·01; 4·0 1·4, 10·4), presence left spontaneous echo contrast (P<0·025; 3·5 1·2, 10·0]), appendage peak velocity ƒ0·20 m . s "1 4·1 11·6]) significantly related Stepwise logistic regression showed independent were: (P<0·005), (P<0·05) low (P<0·01). Conclusions In fibrillation, atrium, particular flow velocity, can be used identify subgroup at either increased decreased risk thromboembolism, which might have important implications anticoagulation therapy. (Eur Heart J 1999; 20: 979‐985)