Development of the 1994 Chronic Fatigue Syndrome Case Definition and Clinical Evaluation Guidelines

摘要: A case definition is a methodologic tool that establishes criteria for classifying (in formal research) or diagnosing clinical practice) of illness disease. Chronic fatigue syndrome (CFS) defined solely on the basis patient-reported symptoms and exclusion, by evaluation, other causes such symptoms. None are specific CFS there no diagnostic confirmatory laboratory tests physical findings (Holmes, 1989; Shafran, 1991; Klonoff, 1992). Because these limitations, published reference definitions have been crucial coordinating research this condition facilitating effective communications among investigators, physicians, patients.