Ankyrin-B metabolic syndrome combines age-dependent adiposity with pancreatic β cell insufficiency

作者: Damaris N. Lorenzo , Jane A. Healy , Janell Hostettler , Jonathan Davis , Jiayu Yang

DOI: 10.1172/JCI81317

关键词:

摘要: Rare functional variants of ankyrin-B have been implicated in human disease, including hereditary cardiac arrhythmia and type 2 diabetes (T2D). Here, we developed murine models to …

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